Nutrition & Fuel
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4 min read
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Pace & Phase Editorial

The diet industry has spent decades vilifying carbohydrates. From keto trends to carnivore diets, women are constantly told that eliminating carbs is the secret to weight loss and hormonal health.
While cutting carbs can yield rapid initial water loss, long-term carbohydrate restriction in active women frequently leads to cold hands and feet, thinning hair, missed periods, high nighttime cortisol, and severe fatigue.
Female biology requires carbohydrates not just for workout fuel, but for basic endocrine function.
The Thyroid Connection: Converting T4 to Active T3
Your thyroid gland is the master thermostat of your metabolism. It produces predominantly inactive hormone called T4 (Thyroxine).
To turn T4 into active T3 (Triiodothyronine)—the hormone that keeps your body warm, drives hair growth, and keeps your metabolism running hot—your liver requires circulating glucose and stored liver glycogen.
When you cut carbs for extended periods, your liver senses glucose deprivation. It slows down the conversion of T4 into active T3, and elevates an inactive blocker called Reverse T3 (rT3). Your metabolic engine slows down to save your life.
Reproductive Health & Kisspeptin Neurons
Your brain contains specialized energy sensors called Kisspeptin neurons. Think of them as a fuel gauge for your reproductive system.
Female kisspeptin neurons are exquisitely sensitive to circulating glucose levels. When you combine strength training or cardio with a low-carbohydrate diet, kisspeptin neurons detect energy scarcity.
They immediately signal your brain to pause ovulation. This leads to low progesterone levels, irregular cycles, or Hypothalamic Amenorrhea (loss of your period). Your body intelligently decides: "We don't have enough glucose to support a potential pregnancy right now."
The Evening Carbohydrate & Sleep Connection
Cutting carbohydrates—especially at dinner—is one of the most common reasons active women suffer from persistent 3 AM sleep disruptions. Falling asleep and staying asleep requires a delicate balance of the neurotransmitters serotonin and melatonin, both of which are synthesized from the essential amino acid tryptophan.
However, for tryptophan to cross the blood-brain barrier efficiently, it needs a small insulin response triggered by carbohydrates. When you consume a cupped-hand portion of complex carbohydrates at dinner (such as sweet potatoes, quinoa, or wild rice), the mild insulin release allows competing amino acids to enter muscle tissue, clearing the pathway for tryptophan to enter the brain. This boosts evening serotonin production, relaxes your central nervous system, and provides steady liver glycogen to prevent nighttime hypoglycemia—keeping you asleep all night.
Liver Glycogen & Ovulatory Health
While your skeletal muscles store glucose to power physical movement, your liver stores glycogen specifically to manage baseline systemic energy and maintain stable blood sugar for your brain while you rest. The female reproductive axis requires a fully stocked liver glycogen pool to signal to the pituitary gland that energy is abundant enough to support a prospective pregnancy.
When liver glycogen drops too low due to chronic low-carbohydrate intake, your liver increases its production of sex hormone-binding globulin (SHBG) and signals energy deficit directly to the hypothalamus. This disrupts the surge of luteinizing hormone (LH) required for follicle rupture, leading to anovulatory cycles (cycles where a period occurs but no egg is released). Including adequate unrefined carbohydrates ensures your liver glycogen remains topped off, protecting both your progesterone production and menstrual regularity.
Complex Carbs vs. Refined Sugar
The goal isn't to live on donuts and pastries. The key is prioritizing unrefined complex carbohydrates that feed your thyroid and gut microbiome without spiking your blood sugar wildly:
Root Vegetables: Sweet potatoes, beets, carrots, squashes.
Whole Grains: Quinoa, oats, brown rice, wild rice.
Legumes: Lentils, chickpeas, black beans.
Whole Fruits: Berries, apples, bananas, oranges.
Aim to include a cupped-hand portion of complex carbs in your post-workout meal and dinner to support nighttime serotonin production and deep sleep.
How Pace & Phase Supports Your Cycle
Pace & Phase never advocates for zero-carb diets. The app helps you time your complex carbohydrate intake around your workouts and cycle phases, keeping your thyroid healthy, your energy high, and your menstrual cycle regular.
Key Vocabulary
Active T3 (Triiodothyronine): The primary active thyroid hormone that drives cellular metabolism, core body temperature, and daily energy.
Thyroid Conversion (T4 to T3): The enzymatic transformation of inactive T4 hormone into active T3, occurring largely in the liver.
Kisspeptin Neurons: Specialized sensors in the brain that monitor glucose levels to control reproductive hormones and ovulation.
Hypothalamic Amenorrhea: The loss of a menstrual cycle caused by energy or carbohydrate deficiency relative to expenditure.
Reverse T3 (rT3): An inactive hormone isomer that blocks active thyroid receptors during severe metabolic stress.












